Position Overview
We are seeking a motivated Research Associate to join our San Carlos team in a hybrid role that combines hands-on bench work with day-to-day management of the lab site. Roughly half the position is at the bench: PBMC isolation, cancer cell and circulating tumor cell (CTC) culture, patient-derived organoids (PDOs) culture, and cell/organoid characterization. The other half focuses on supporting laboratory operations: purchasing, inventory, specimen logistics, vendor and facility coordination, scheduling, and documentation. The work supports the company's research programs in 3D cell culture and translational model development. The ideal candidate works well in a small team, can own the operational side with limited supervision, and adapts as priorities shift.
About AcroCyte
AcroCyte Therapeutics is a pioneer in advanced translational medicine, leading the development of next-generation scaffold-free 3D organoid cultures derived from human patient samples. By bridging the gap between complex in vitro models and clinical reality, we are driving the future of next-generation liquid biopsy platforms and precision oncology to accelerate therapeutic discovery and patient care.
Key Responsibilities
Research
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Culture, expand, and characterize primary cells, spheroids, and PDOs on both 2D and 3D platforms
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Isolate PBMCs from whole blood by density gradient centrifugation and related methods
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Maintain kidney cell and renal organoid cultures for the company's autologous renal cell therapy program
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Process and handle patient specimens, including intake, documentation, and chain of custody
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Maintain aseptic technique across routine cell culture operations
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Prepare samples for downstream analysis (e.g., immunostaining, flow cytometry, DNA and RNA extraction)
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Perform viability assessment, brightfield and fluorescence imaging, and organoid characterization
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Record experimental procedures and results in the electronic laboratory notebook (ELN)
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Execute experiments to written protocols, draft and revise SOPs for the assays you run
Laboratory Operations and Administration
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Own purchasing end to end: obtain quotes, place orders, track and reconcile shipments
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Maintain reagent, consumable, and cell inventories, and keep freezer and cold-storage records current
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Prepare reagents, media, and buffers, and maintain the associated lot and expiration records
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Arrange incoming and outgoing shipments of biological specimens
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Maintain laboratory safety and compliance records (e.g., chemical inventory, biosafety documentation)
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Contribute flexibly to other research and operational tasks as priorities shift in a startup setting
Minimum Qualifications
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Bachelor's degree in Biology, Chemistry, Chemical Engineering, Bioengineering, Biotechnology, Immunology, or a related life-science field
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1–3 years of hands-on mammalian cell culture experience
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Demonstrated experience with sterile technique and routine culture maintenance
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Strong organizational skills and attention to detail in documentation and record-keeping
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Ability to communicate clearly and work effectively as part of a small team in a fast-paced environment
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Willingness to take on administrative and operational responsibilities alongside bench work
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Availability for recurring video meetings with the Taiwan team outside standard Pacific hours, typically in the evening (Mandarin is not required)
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Comfortable handling human blood and clinical specimens under standard biosafety practice
Preferred Qualifications
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Hands-on experience handling and processing human blood samples (PBMC isolation, plasma collection, etc.)
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Experience with primary cell culture, cancer cell culture, or CTC culture
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Experience with kidney cell culture, renal progenitor cells, or kidney organoids
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Experience with 3D cell culture systems (e.g., spheroid, organoid, scaffold-free, and hydrogel-based platforms)
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Familiarity with ELN systems and lab inventory management
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Experience with immunostaining, flow cytometry sample preparation, DNA and RNA extraction, RT-PCR
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Experience working in a regulated laboratory environment (e.g., CLIA, CAP, ISO 15189, or equivalent) with demonstrated attention to quality, documentation, and data integrity
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Experience supporting clinical, translational, or diagnostic laboratory operations in a regulated setting
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Experience with laboratory purchasing, inventory systems, or lab management responsibilities
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Prior experience in a startup or fast-paced biotech environment
What We’re Looking For
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Medical, dental, and vision coverage
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Paid time off and company holidays
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The opportunity to shape an early-stage platform technology and grow with the company
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A collaborative, cross-functional team spanning the U.S. and Taiwan
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Direct exposure to precision-medicine, liquid-biopsy, and regenerative-medicine science
How to Apply
Send your resume and a short note describing your relevant cell culture and laboratory operations experience to buddy@acrocyte.com.
Please include the position title in the subject line.