Application

Explore the boundaries of science with R3CE

Our three main areas of application: replacing animal experiments, implementing precision medicine, and accelerating regenerative medicine.​

R3CE ex vivo model​

View spheroids from all sample sources in our gallery​

Colorectal cancer, breast cancer, urothelial cancer paired normal/tumor spheroid bank, as well as rapid PDx formation available.​

Upper-Tract Urothelial Carcinoma Tissue

Upper-Tract Urothelial Carcinoma Tissue

Upper-Tract Urothelial Normal Tissue

Upper-Tract Urothelial Normal Tissue

Breast Tumor Tissue

Needle-Biopsy Breast Tumor Tissue

Breast Normal Tissue

Needle-Biopsy Breast Normal Tissue

Colorectal Tumor Tissue

Surgical Colorectal Tumor Tissue

Colorectal Normal Tissue

Surgical Colorectal Normal Tissue

TOV-112D

Ovarian Cancer

TOV-21G

Ovarian Cancer

SKOV-3

Ovarian Cancer

T24

Urothelial Carcinoma

MDA-MB-231

Breast Cancer

H1975

Non-small-cell Lung Cancer

H1299

Non-small-cell Lung Cancer

SAS

Head and Neck Squamous Cell Carcinoma

WiDr

Colorectal Cancer

HCT15

Colorectal Cancer

HCT116

Colorectal Cancer

Upper-Tract Urothelial Carcinoma Tissue
Upper-Tract Urothelial Carcinoma Tissue
Upper-Tract Urothelial Normal Tissue
Upper-Tract Urothelial Normal Tissue
Breast Tumor Tissue
Needle-Biopsy Breast Tumor Tissue
Breast Normal Tissue
Needle-Biopsy Breast Normal Tissue
Colorectal Tumor Tissue
Surgical Colorectal Tumor Tissue
Colorectal Normal Tissue
Surgical Colorectal Normal Tissue
TOV-112D
Ovarian Cancer
TOV-21G
Ovarian Cancer
SKOV-3
Ovarian Cancer
T24
Urothelial Carcinoma
MDA-MB-231
Breast Cancer
H1975
Non-small-cell Lung Cancer
H1299
Non-small-cell Lung Cancer
SAS
Head and Neck Squamous Cell Carcinoma
WiDr
Colorectal Cancer
HCT15
Colorectal Cancer
HCT116
Colorectal Cancer
Upper-Tract Urothelial Carcinoma Tissue
Upper-Tract Urothelial Carcinoma Tissue
Upper-Tract Urothelial Normal Tissue
Upper-Tract Urothelial Normal Tissue
Breast Tumor Tissue
Needle-Biopsy Breast Tumor Tissue
Breast Normal Tissue
Needle-Biopsy Breast Normal Tissue
Colorectal Tumor Tissue
Surgical Colorectal Tumor Tissue
Colorectal Normal Tissue
Surgical Colorectal Normal Tissue
TOV-112D
Ovarian Cancer
TOV-21G
Ovarian Cancer
SKOV-3
Ovarian Cancer
T24
Urothelial Carcinoma
MDA-MB-231
Breast Cancer
H1975
Non-small-cell Lung Cancer
H1299
Non-small-cell Lung Cancer
SAS
Head and Neck Squamous Cell Carcinoma
WiDr
Colorectal Cancer
HCT15
Colorectal Cancer
HCT116
Colorectal Cancer

No more rare cell problem​

R3CE is compatible with all molecular analysis pipelines ​

Immunostaining of Colorectal Cancer tumoroid cultured on R3CE​

Top-down sectioning​
Middle-down sectioning​
Single Cell PCR​
qPCR
Immunostaining
Flow Cytometry
And many more!

Immunostaining of cultured CTCs

Blood Sample: Breast cancer patient (HER2 3+; ER 90%; PR 5%)
EpCAM/PanCK/CD45
Her2/ER
Her2/PR

Drug Testing for REAL

Rapid Easy Accurate Limitless
oncology drug testing platform ​

Rapid

In time for clinical decision (2~3 weeks)​

Easy

Blood draw for 2 vials (~20 ml)​

Accurate

>90%
clinical concordance​

Limitless

Repeatable rare cell cultures from blood, no surgery needed​

Drug testing platform utilizes AcroCyte’s core technology R3CE and can be the gateway to further insights on anticancer drug reaction and efficacy. See our workflow and further applications below, or contact us for more information.​

Drug test workflow achievable in less than one month​

Drug Test Leads to Reduced Cell Viability

Same patient-derived R3CE breast cancer CTC and tumor cell both show reduced cell viability after drug test ​

Mock​
Drug Test​
CTCs ​
Tumor cells ​ ​
Mock​ CTCs
Mock​ Tumor cells ​ ​
Drug Test​​ CTCs
Drug Test​​ Tumor cells ​ ​

Active clinical sites

Regenerative medicine​

R3CE can generate spheroids even if the initial cell counts are low, making it a perfect fit for culturing stem cells

Single cell proliferation of Wharton's jelly-Mesenchymal stem cells (WJ-MSC) on R3CE​
R3CE is free of bio-derived components and compatible with all regenerative technologies. All R3CE products are produced in certified labs to ensure top-notch quality control. ​

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Work with us​

R3CE PLATFORM ​

Featured work:
‍building the leading patient-derived cancer cell bank in Asia with NLAC

National Laboratory Animal Center (NLAC), established under the guidance of the Taiwan‘s National Science and Technology Council, is the largest and internationally-qualified official animal resource center and laboratory in Taiwan. Together with NLAC, we are currently operating a joint Tumor Organoid Laboratory, and building a PDx (PDO, PDS) Bank from multi-source cancer patient samples. By leveraging AcroCyte’s 3D culture capabilities, we can increase successful rate in PDx, PDO, and PDS models with low initial seeding, taking strides towards making precision medicine more accessible to all.

Further cooperation with us
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